Tight Glucose Control Raised Mortality in ICU
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منابع مشابه
Essential elements of the native glucoregulatory system, which, if appreciated, may help improve the function of glucose controllers in the intensive care unit setting.
In 2001, Van den Berghe and colleagues were able to show that tight glucose control decreases morbidity and mortality rates in the intensive care unit (ICU) setting. Several large, prospective, randomized controlled trials have failed to confirm these results. All of these studies attempted tight glucose control using expert-designed algorithms to adjust the rate of intravenous insulin. Unfortu...
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INTRODUCTION : The 2001 van den Berghe et al. study showed that intensive glucose control reduced mortality. Subsequent large randomized controlled trials of tight glucose control have failed to show a mortality benefit. Consequently, considerable controversy has emerged as to whether tight glucose control is warranted in all critically ill adults. Differences between studies have been explaine...
متن کاملRE: Revisiting tight glycemic control in perioperative and critically ill patients: when one size may not fit all.
Glycemic control has received intense scrutiny in the last decade as an important aspect of patient care. Earlier studies suggested that tight glycemic control (target level of 80 - 110 mg/dL) improved outcomes in intensive care unit (ICU) patients. Subsequent trials did not confirm the same benefit. Moreover, increased mortality was found in association with such tight control compared with a ...
متن کاملIntensive insulin protocol improves glucose control and is associated with a reduction in intensive care unit mortality.
BACKGROUND Intensive insulin therapy to maintain serum glucose levels between 80 and 110 mg/dL has previously been shown to reduce mortality in the critically ill; recent data, however, have called this benefit into question. In addition, maintaining uniform, tight glucose control is challenging and resource demanding. We hypothesized that, by use of a protocol, tight glucose control could be a...
متن کاملProfile and long-term prognosis of glucose tight control in intensive care unit - patients: a cohort study.
OBJECTIVES Stress-induced hyperglycemia is frequent in critically ill patients and has been associated with increased mortality and morbidity (both in diabetic and non-diabetic patients). This study objective was to evaluate the profile and long-term prognosis of critically ill patients undergoing tight glucose-control. METHODS Prospective cohort. All patients admitted to the intensive care u...
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